A novel inducible acute hyperglycemia mouse model for assessing 6‑KTP
نویسندگان
چکیده
منابع مشابه
Establishment of a novel rat model of severe acute cholangitis
Objective(s):This study aimed to establish a novel non-binding, reversible rat model of acute cholangitis of the severe type (ACST). Materials and Methods:Twenty-six rats were randomly divided into the sham-operated group (n=13) and the ACST group (n=13). All rats were intubated with a modified catheter through the external jugular vein. The ACST model was established by ligation of the distal ...
متن کاملiRAGu: A Novel Inducible and Reversible Mouse Model for Ubiquitous Recombinase Activity
Developing lymphocytes express the recombination activating genes (RAGs) 1 and 2 products that form a site specific recombinase complex (RAG), introducing double strand DNA breaks (DSBs) at recombination signal sequences (RSSs) flanking the V, D, and J gene segments in the antigen receptor loci. The subsequent steps in the reaction consist in the ligation of DSBs by ubiquitous enzymes of the no...
متن کاملIncreased atherosclerotic lesion calcification in a novel mouse model combining insulin resistance, hyperglycemia, and hypercholesterolemia.
No mouse model is currently available where the induction of type 2 diabetes on an atherosclerotic background could be achieved without significant concomitant changes in plasma lipid levels. We crossbred 2 genetically modified mouse strains to achieve a model expressing both atherosclerosis and characteristics of type 2 diabetes. For atherosclerotic background we used low-density lipoprotein r...
متن کاملA transgenic mouse model for inducible and reversible dysmyelination.
Oligodendrocytes are glial cells devoted to the production of myelin sheaths. Myelination of the CNS occurs essentially after birth. To delineate both the times of oligodendrocyte proliferation and myelination, as well as to study the consequence of dysmyelination in vivo, a model of inducible dysmyelination was developed. To achieve oligodendrocyte ablation, transgenic animals were generated t...
متن کاملA functional model for assessing Iran's cinematic websites
Background and Objectives: Today, websites with diverse and varied uses have revolutionized all social, scientific, educational, artistic, commercial, and other fields of thought. In the meantime, the cinema has not gone away with this technological advancement, and a large number of cinema websites have been set up to help film makers in this field. Whatever the users of a website, the main pu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomedical Reports
سال: 2019
ISSN: 2049-9434,2049-9442
DOI: 10.3892/br.2019.1228